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Anxious Depression Treatment

Treatment For When Relief Feels Out Of Reach

Are you struggling with a mix of low mood and constant tension? Do you feel weighed down by depression, yet restless or on edge at the same time?

This experience has a name: major depression with anxious distress. And it’s more common than most people realize.

At Paxina, we recognize how these symptoms often overlap and go unrecognized. That’s why we take an integrative approach to care—one that addresses both the depressive symptoms and the anxiety beneath them.

What Is Major Depression With Anxious Distress?

Major depression with anxious distress isn’t just feeling low or stressed. It’s depression combined with ongoing anxiety. It’s also one of the most commonly missed presentations of depression.

At Paxina Health, we understand this experience deeply and approach it as a real, complex, and treatable condition—one that deserves careful attention, thoughtful planning, and a treatment approach that supports both sides of what you’re feeling.

Common Symptoms of Major Depression With Anxious Distress

You might be experiencing major depression with anxious distress if:

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You Feel Stuck

It’s more than sadness. It’s a heavy, restless tension that never fully lifts. Even when things are “fine,” your mind won’t stop scanning for what might go wrong next

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You’re Overwhelmed

You may feel keyed up, easily startled, or unable to relax—even when you’re exhausted. The depression weighs you down, while the anxiety keeps your nervous system on high alert.

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You Experience Spiraling Thoughts

You ruminate constantly. Worry and guilt are persistent. And even small decisions feel paralyzing. This is what happens when anxiety hijacks the thought process, especially in someone already dealing with depression.

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You Feel Like You’re Failing—No Matter What You Do

Living with both depression and anxiety can lead to intense self-doubt. You may push yourself to keep going, even when you're running on empty, and still feel like it's never enough.

Why Conventional Treatment Doesn’t Always Work

When depression and anxiety show up together, they don’t just add up—they interact. And that interaction can make both harder to treat.

Many patients come to us after trying therapy, medication, or both, and still not feeling like themselves. Here’s why:

Medications Don’t Fully Address Your Symptoms

Most antidepressants are designed to lift mood. But for people whose depression includes significant anxious distress, medication alone may not fully address the internal tension, restlessness, or racing thoughts.

Therapy Only Takes You So Far

Talk therapy can be transformative. But when your nervous system is constantly on edge or your brain chemistry is out of balance, insight alone may not be enough. You might understand your patterns—and still feel stuck in them.

Symptoms Get Misread

People with anxious distress often push through. You might appear high-functioning on the outside, while privately experiencing overwhelming fatigue, fear, or hopelessness. That can make it harder to get the right diagnosis, or the right treatment.

At Paxina, we take a more nuanced approach. Conventional treatment isn’t wrong; it’s just incomplete for some people. That’s why we offer expanded options, tailored to your needs, your symptoms, and your goals.

How Paxina Health Helps

At Paxina, we specialize in treating depression that doesn’t show up in textbook ways. When anxiety is layered into the experience, we take extra care to build a plan that supports both your mood and your ability to settle, focus, and function.

Our integrated treatment options include:

Transcranial Magnetic Stimulation (TMS)

This non-invasive, FDA-approved treatment uses magnetic pulses to stimulate mood-regulating areas of the brain. TMS is especially helpful for patients whose symptoms haven’t responded to medication alone.

Learn More About TMS

SPRAVATO® (Esketamine Nasal Spray)

For adults with treatment-resistant depression, SPRAVATO® offers a different mechanism of action. It’s administered in our clinic under medical supervision and is often described by patients as a turning point—especially when anxiety complicates the picture. Expected availability in March 2026.

Is SPRAVATO® Right for You?

General Psychiatry & Medication Management

Our approach to psychiatry is collaborative and thoughtful. We work with you to review your treatment history, clarify your diagnosis, and adjust your medication (if needed) with your full input. For many, this becomes the foundation for sustained progress, especially when paired with interventional therapies. Expected availability in March 2026.

Explore Our Psychiatry Services

What You Can Expect From Us

Living with depression that includes anxious distress can feel confusing, exhausting, and often misunderstood. At Paxina, we do things differently. Our approach is personal, layered, and designed to meet you exactly where you are.

Here’s what you can expect

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Thorough Evaluation

We start by understanding your full story—not just your symptoms. That means reviewing your treatment history, current challenges, and goals. Every decision stems from a deep understanding of who you are.

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Tailored Treatment Plan

There’s no one-size-fits-all path. Depending on your needs, we may recommend TMS, SPRAVATO®, medication adjustments, or a combination of approaches. We’ll walk through every option together so you feel confident in the plan.

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Collaborative Support

You’ll never be left to figure things out on your own. We check in regularly, listen closely, and adjust when needed to ensure your care stays aligned with how you’re actually feeling.

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A Focus on Real Relief

Our goal isn’t just fewer symptoms—it’s helping you feel lighter, more connected, and more like yourself again. Many patients tell us it’s the first time they’ve felt understood, not just treated.

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Why Patients Trust

Paxina Health

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Your Care Comes First

Too many interventional clinics are built around volume, not people. At Paxina, your care comes first. We never recommend treatments that aren’t right for you, and we never rush the process. Every decision, from the treatment approach to the pace of your care, comes back to one question: what is truly best for you?

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You’ll Be Heard, Never Rushed

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An Environment That Supports Healing

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Physician-Led Treatment

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Who We Are

Paxina Health was founded by psychiatrists Dr. Todd Young and Dr. Nicodemus Watts with a shared mission: to create a practice where patients are truly seen, heard, and cared for.

Here, recovery starts with compassion, grows with understanding, and evolves as your needs change.

Meet the Paxina Team
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Healing Starts Here

Wherever you are on your journey, Paxina is ready to help you heal the whole you. All you have to do is take the first step by reaching out.

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Address:

12625 High Bluff Drive, Suite 111, San Diego, CA 92130

Hours

Monday - Friday 9 am - 5 pm


Contact:

619.566.1002 office
619.566.1003 fax

contact@paxinahealth.com

©2026 Paxina Health. All rights reserved.